novel medicine for all

At the RNAImmune, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.

RNAImmune discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, infectious diseases and vaccines.

Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.

 
 

About

RNAimmune is a biotechnology startup in the field of messenger RNA (mRNA) technology with more than 20 years’ expertise in handling and optimizing this versatile molecule for medical purposes. The principle of RNAimmune's proprietary technology is the use of mRNA as a data carrier to instruct the human body to produce its own proteins capable of fighting a wide range of diseases. The company applies its technologies for the development of cancer therapies, antibody therapies, the treatment of rare diseases, and prophylactic vaccines.

Our science

 

mRNA Design Platform

We’ve developed a synthetic biology based, artificial intelligence aided platform that help us design better mRNAs to invoke the optimal response from our immune system. Current projects that are enabled by our platform include multi-target prophylactic vaccines and cancer vaccines expressing tumor-targeted epitopes.


Proprietary Delivery

Using our proprietary Polypeptide Lipid Nanoparticle (PLNP) based carrier, we are able to deliver a wider variety of mRNAs with enhanced intracellular expression.


Self-amplifying mRNA

Our novel self-amplifying mRNAs provide stronger and longer potency for each treatment.

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Focus Areas

Infectious Diseases

We develop prophylactic vaccines to help immune systems build responsive mechanisms against serious infectious diseases.


Immuno Oncology

We develop individualized neoantigen based therapeutic vaccines to treat cancer. We also provide early detection and companion diagnosis


Rare Diseases

We develop mRNA-based therapeutics to treat difficult rare diseases.

 
 

team

 
 

Dong Shen, M.D., Ph.D. — Chief executive officer

Dr. Shen graduated with PhD degree from Johns Hopkins University School of Medicine and MD degree from Shanghai Jiao Tong University School of Medicine. Dr. Shen has extensive drug development experience in AstraZeneca and Johnson and Johnson, having led projects across multiple therapeutic areas with high unmet medical need. He has held leadership across early and late programs in the areas of infectious disease, oncology and rare disease. Dr. Shen received numerous awards in the past. He was the recipient of Johnson & Johnson leadership award in 2018 and innovation award in 2017. All his manuscripts have been published at the most influential journals, such as Science and Nature. The total number of his publication citations is over 16,400.

ZHIFENG (STEVEN) LONG, PH.D. — CHIEF SCIENCE OFFICER

Steven received his Ph.D. in Genetics from Leeds University in England in 1987. Steven has 30+years of experience in the pharmaceutical industry. Since 1989 he has held key positions atApptec (now Wuxi Apptec), Genetic Therapy, Sandoz, Novartis, AnGes, Personal Diagnostix, and Sirnaomics. He served as VP for CMC at Sirnaomics in 2018 – 2021 and Chief Development Officer in 2021 – 2023. He was responsible for the successful development of STP707, a novel polypeptide nanoparticle drug product containing siRNAs that is now being studied in the clinics for solid tumors including liver cancer. He also led the manufacturing development of applying microfluidic mixing process in GMP production of STP705 in 2019.

Kevin he, M.D, Ph.D — Chief medical officer (CHINA)

Dr Jiaxi He received his medical degree from Sun Yat-Sen University and Guangzhou Institute of Respiratory Disease in Thoracic Oncology and Respiratory Disease. He was a postdoc research fellow in University of Maryland focusing on nucleic acid delivery system and gene therapy. Dr. He is a certified thoracic surgeon, pulmonologist and oncologist in China with abundant clinical experience. He has published over 60 papers in high quality international journals including JCO, JSO, Lung Cancer, et.al and given oral presentations in various international conferences. He is a reviewer and editor of Frontiers and AME Publication Company. Dr. He was awarded as the most promising youth oncologist in the 2nd “35 under 35” Outstanding Youth Oncologist Talent Competition by Chinese Society of Clinical Oncology in 2018. He is one of the co-founder of RNAimmune and is leading the R&D team of RNAimmune Guangzhou. 

Stanley He, MBA — Chief Business Officer

Stanley has over 5 years of diverse experience in the startup and investment space. Prior to joining RNAimmune, Stanley was an Investment Associate at Principle Capital, a boutique private equity firm in Shanghai. Stanley is also an avid individual investor who focuses on publicly-listed biotech companies and seed-stage consumer tech companies. Stanley received his B.S. in Business Administration from Babson College and received his MBA from Georgetown University.

nigel yip, MBA — Chief finance officer

Nigel has 10+ years of transaction experiences in merger & acquisitions, initial public offerings, and private equity. Prior to joining Sirnaomics, Nigel served as a vice president in the Credit Suisse’ investment banking team, and later transferred to Credit Suisse’ private equity team covering growth equity opportunities across healthcare, consumer, and technology sectors in Asia Pacific. In his current role, Nigel manages the overall fundraising process of the group and communication with the banking and investor communities.

Contact

 

Address

20511 Seneca Meadows Parkway, STE 260
Germantown, MD 20876

Contact

hello@rnaimmune.com